Patients with axial spondyloarthritis: Five year observation study
Research type
Research Study
Full title
Patients with axial spondyloarthritis: multicountry registry of clinical characteristics, including radiographic progression, and burden of disease over 5 years in real-life setting
IRAS ID
144120
Contact name
Pauline Ho
Contact email
Sponsor organisation
Abbvie Ltd
Research summary
This five-year study will aim to measure the number of patients attending rheumatology clinics in the UK with unexplained chronic back pain (back pain that has lasted for three months or more) who are diagnosed with either AS (ankylosing spondylitis) or nr-axSpA (non-radiographic ax-SpA) using the Assessment of Spondyloarthritis international Society (ASAS) criteria. AS and nr-axSpA are both types of arthritis that affect parts of the spine.
The study will go on to collect data on patients with these conditions in a clinical setting, over a 5 year period.
Participants will be recruited from rheumatology clinics and those who are diagnosed with either AS or nr-axSpA will complete four questionnaires and one rating scale once a year during a routine rheumatology clinic visit, over the five year period of the study.
The questionnaires and rating scale will measure how much the disease has affected the patient, what physical activities the patient can or cannot do, the patient’s quality of life, how much the disease interferes with working, and how active on a scale of one to ten the patient believes their disease has been.
During routine annual visits over the five years of the study, the patient’s doctor will also collect information about their referral history and details about the patient (including treatment information, whether the patient has other illnesses , their assessment of the patient’s disease and what medication the patient is currently on).REC name
London - Chelsea Research Ethics Committee
REC reference
14/LO/0231
Date of REC Opinion
3 Mar 2014
REC opinion
Favourable Opinion