Patients' view to improve compliance to gluten free diet.
Research type
Research Study
Full title
Patients' view to Improve Compliance to Gluten Free Diet in Coeliac Disease.
IRAS ID
177503
Contact name
Humayun Muhammad
Contact email
Sponsor organisation
Roehampton University
Clinicaltrials.gov Identifier
University Hospitals of Leicester Ethics Ref No, UHL 11418; University of Roehampton, LSC 15/ 130
Duration of Study in the UK
0 years, 6 months, 7 days
Research summary
Coeliac disease (CD) is a disorder of the gastrointestinal system where an allergic reaction to gluten (found in wheat and related products) leads the inflammation of the inner lining of the small bowel. This in turns leads to mal-absorption resulting in anaemia, and may lead to skin disorder, cancer and bone disease. Avoiding gluten is the only practical way to counteract this allergic reaction. Patients with coeliac disease are offered strict Gluten free diet (GFD).
The diet itself is not easy to follow and there are compliance related issues in patients with CD. There is evidence to suggest that compliant patients have less complication in long run. Compliance is low in Asian patients as shown by one previous study in 2004 (Butterworth et; al) and subsequently in my recent project where questionnaire was administered to 975 patients.
There is only one Australian study (Sainsbury and Mulan 2013) which designed and administered an intervention to increase compliance in CD. We can improve the design of this study and conduct an interview of the non-compliant patients to design and intervention which is cheap and easily administrable. In addition to that no intervention has been specifically designed for ethnic minority who does not speak English.
This research will first administer a 20-30 minutes interview both in English and ethnic languages and with the help of the information will design an intervention to increase compliance to Gluten Free Diet (GFD). We have already identified 155 non-compliant patients who could be approached for this purpose through invitation letter as potential participants for telephonic interview. The response rate is expected to be good as these patients have already been engaged through our first questionnaire based study. The research is low risk and involves qualitative methods.REC name
Yorkshire & The Humber - Sheffield Research Ethics Committee
REC reference
15/YH/0289
Date of REC Opinion
18 Jun 2015
REC opinion
Further Information Favourable Opinion