Patient self-assessment in Psoriatic Arthritis (P_saPsA)
Research type
Research Study
Full title
Patient self-assessment in Psoriatic Arthritis (P_saPsA)
IRAS ID
240090
Contact name
Philip Helliwell
Contact email
Sponsor organisation
Bradford Teaching Hospitals NHS Foundation Trust
Clinicaltrials.gov Identifier
n/a, n/a
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
The natural course of inflammatory arthritides, including psoriatic arthritis (PsA), has periods of flare and remission. The assessment of flares is useful to understand disease status and treatment efficacy. The inflammation characterised by a flare causes pain, swelling and disability and can lead to long term joint damage. There is extensive evidence that prompt management of flares has long-term benefits. Inflammation in PsA presents itself in the form of tender and/or swollen joints, enthesitis, dactylitis, spondylitis and nail disease, the assessment of which requires patient attendance at hospital and assessment by a healthcare professional. Hospital attendance is usually driven by scheduled appointments rather than by flare so opportunities for effective management may be missed. \n\nThe Psoriatic Arthritis Disease Activity Score (PASDAS) instrument was developed to measure all the domains of PsA inflammation but it is labour intensive to complete and complicated to calculate, making it impractical for use in a busy clinic. However, the comprehensiveness of the PASDAS also provides the perfect basis for the development of an instrument that employs patient completed aspects of inflammation. A patient driven disease activity instrument has been developed for RA and has demonstrated an acceptable level of agreement with clinical assessment.\n\nIn this study, we propose to develop a self-assessment tool for PsA patients based upon the PASDAS. We will invite rheumatology patients from Bradford and Leeds to participate. Patient focus groups will first review and modify the components of the PASDAS to facilitate patient self assessment. We will then develop an instrument based upon the focus group feedback and mail this instrument to a cohort of patients to self complete at home prior to their routine clinic visit. The results of their self assessment of their inflammation will then be compared with the clinicians assessment using the same instrument plus other clinical makers.\n
REC name
London - South East Research Ethics Committee
REC reference
18/LO/0889
Date of REC Opinion
17 May 2018
REC opinion
Favourable Opinion