Passive Fluenz Tetra Safety Surveillance

  • Research type

    Research Study

  • Full title

    Passive Enhanced Safety Surveillance (ESS) of the Quadrivalent Live Attenuated Influenza Vaccine (QLAIV) Fluenz Tetra in Children and Adolescents during the early 2015/2016 Influenza Season in England

  • IRAS ID

    183946

  • Contact name

    Saad Shakir

  • Contact email

    saad.shakir@dsru.org

  • Sponsor organisation

    Drug Safety Research Unit

  • Duration of Study in the UK

    0 years, 6 months, 31 days

  • Research summary

    This is a passive enhanced safety surveillance (ESS) project on the live-attenuated nasal influenza vaccine, Fluenz Tetra®. The aim of the surveillance is to rapidly detect changes in the frequency or severity of reactions to the vaccination in children during the 2015/2016 influenza season. The surveillance is being conducted to satisfy the European Medicines Agency's (EMA) requirement for enhanced safety surveillance for seasonal influenza vaccines in the EU. Children will be provided with a Safety Report Card with an integrated consent form following vaccination for completion by their parents in the event that any suspected side effects are experienced. Any data received will be collated and analysed and a report for the EMA will be written 6 weeks after the first vaccination.

  • REC name

    North West - Liverpool Central Research Ethics Committee

  • REC reference

    15/NW/0656

  • Date of REC Opinion

    17 Aug 2015

  • REC opinion

    Further Information Favourable Opinion