PARADIGM study version 1
Research type
Research Study
Full title
Parkinson’s disease: Risk Assessment of Persistent Delirium and its Management (PARADIGM study)
IRAS ID
293560
Contact name
William Lee
Contact email
Sponsor organisation
Newcastle University
Duration of Study in the UK
3 years, 7 months, 30 days
Research summary
Importance
Delirium describes the change in people’s behaviour and thinking when they are unwell. People with delirium may appear confused, have difficulty with organisation and can be different to their usual personality.
Older people with Parkinson’s are particularly susceptible to persistent delirium, which can last over 14 days. They are more likely to need increased community support and they have a greater risk of death and dementia. However, there is limited research for people with Parkinson’s on how to effectively manage persistent delirium and how to identify those at risk of persistent delirium. Community support may not sufficiently support the care needs of people with Parkinson’s, and this is expected to be more detrimental for people also affected by persistent delirium.
Objectives
1. To develop a tool that can determine the risk of developing persistent delirium in people with Parkinson’s, so that strategies can be developed in the future to prevent or minimise the adverse consequences of persistent delirium.
2. To evaluate the different approaches used to manage delirium, which will facilitate the future development of an effective care plan.
3. To understand the care needs of people with Parkinson’s affected by persistent delirium, so that community support can be tailored to their specific needs.
Study Design
Information will be collected from Airedale Hospital medical records during 2015-2019. Participants will be aged 65 years and older, with a diagnosis of Parkinson’s. Information will be collected about their age, their symptoms, and the treatments that they have received. This information will be used to develop the care plan and assessment tool. 1 hour, individual interviews of up to 20 participants will involve a discussion of their care needs and the support that they received from social networks and NHS community services. The total project length is 3-4 years.
REC name
Yorkshire & The Humber - Leeds East Research Ethics Committee
REC reference
21/YH/0288
Date of REC Opinion
17 Dec 2021
REC opinion
Further Information Favourable Opinion