Papillon-Lefevre Neutrophil Study

• Research type

  Research Study

• Full title

  Papillon-Lefevre Neutrophil Study

• IRAS ID

  161681

• Contact name

  Michael Dudley

• Contact email

  m.dudley@bham.ac.uk

• Duration of Study in the UK

  0 years, 2 months, 19 days

• Research summary

  Papillon-Lefevre Syndrome (PLS) is an extremely rare inherited autosomal recessive disease characterised by a diffuse palmoplantar keratosis and early onset, severe periodontal destruction leading to premature and permanent loss if of teeth. This study aims to compare the functional abilities of neutrophils from PLS patients to those of healthy controls.

• REC name

  West Midlands - Black Country Research Ethics Committee

• REC reference

  14/WM/1175

• Date of REC Opinion

  10 Oct 2014

• REC opinion

  Further Information Favourable Opinion