PAPERPAC
Research type
Research Study
Full title
PAPERPAC:PAtient PERceptions of long term surveillance in PAncreatic Cancer
IRAS ID
152934
Contact name
Stephen Pereira
Contact email
Sponsor organisation
University College London
Duration of Study in the UK
3 years, 0 months, 1 days
Research summary
Background to the study: Pancreatic cancer is associated with a very poor prognosis, 5 year survival in the UK is <4%. However, if diagnosed early prognosis improves significantly (up to 60% 5 year survival for tumours <2cm). A proportion of individuals have an increased risk of developing pancreatic cancer due to a strong family history or because of a pre-malignant lesion within the pancreas e.g. a mucinous pancreatic cyst. These patients are offered surveillance with cross-sectional imaging or endoscopic ultrasound in accordance with international guidance. How patients find their surveillance experience, if they find it reassuring or anxiety provoking and how they assess their cancer risk is largely unknown.
Study aim: The aims of this study are to evaluate how patients undergoing pancreatic surveillance assess their level of cancer risk and explore how this differs between patients, how it changes over time and if it is influenced by different personal characteristics or management strategies.
Relevance and importance to patients and the public: The information from this study will inform the improvement of future pancreatic surveillance services.
Who is eligible: Patients at an increased risk of developing pancreatic cancer who have been offered pancreatic surveillance.
Sites: The study will be conducted at 6 sites in the UK and 2 in Europe who have a large cohort of patients under regular pancreatic surveillance.
Study Duration: The study aims to recruit 300 patient over 2 years, beginning in Summer 2015 (patients will remain in the study for 12 months so the study will run for 3 years in total).
REC name
North West - Greater Manchester West Research Ethics Committee
REC reference
15/NW/0729
Date of REC Opinion
8 Sep 2015
REC opinion
Favourable Opinion