PAD BIRD
Research type
Research Study
Full title
Peripheral Arterial Disease Biomarkers: The effect of Intervention on biomarker levels and predictors of Restenosis or Deterioration (PAD BIRD)
IRAS ID
323948
Contact name
Philip Stather
Contact email
Sponsor organisation
Norfolk and Norwich University Hospital NHS Foundation Trust
Duration of Study in the UK
3 years, 0 months, 1 days
Research summary
Several studies have identified markers in the blood (called biomarkers) that are associated with peripheral arterial disease, or clogging up of the blood supply to the leg. There is little understanding however regarding how these respond to intervention, and how they are related to walking distance.
This study will increase the understanding of the relationship between peripheral arterial disease state and biomarker expression and enable us to work towards the development of new targets for treatment.
Participants will be invited to undertake questionnaires and dedicated walking tests alongside regular blood tests to check their biomarker levels. These will be undertaken on a regular basis so we can see what happens over time, such as after a surgical procedure, and see if these markers go back towards normal following intervention.REC name
North East - Newcastle & North Tyneside 2 Research Ethics Committee
REC reference
23/NE/0230
Date of REC Opinion
15 Jan 2024
REC opinion
Further Information Favourable Opinion