PACE
Research type
Research Study
Full title
The impact of continuous glucose monitoring with a predictive hypoglycaemia alert function on hypoglycaemia in physical activity for people with type 1 diabetes
IRAS ID
259691
Contact name
Neil Hill
Contact email
Duration of Study in the UK
0 years, 11 months, 31 days
Research summary
Summary of Research
This study aims to assess the impact of Dexcom G6 RT-CGM with a predictive hypoglycaemia alert function on the frequency, duration and severity of hypoglycaemia occurring before, during and after regular physical activity in people with type 1 diabetes. The study duration for each participant will be approximately 90 days and will include use of dexcom both with and without the predictive hypoglycaemia alert function. The research will be carried out at Imperial College Research facility at Hammersmith Hospital, with participants recruited from St Mary's and Charing Cross Hospital.Summary of Results
24 participants were randomised. The participants (8 men, 16 women) had a mean (SD) age of 35 (11) years, duration of diabetes of 14 (7) years, BMI 26 (4.7)kg/m2 and HbA1c of 58 (12) mmol/mol]. 1 person was excluded from the analysis due to incomplete data. The baseline median percentage time < 3.0mmol/l was 0.25 (0.05-0.89)%. At the end-point the percentage time <3.0mmol/l was significantly lower with urgent low soon alerts on (median treatment difference 0.12% (95% CI 0.04-0.2, p=0.0036), compared to the urgent low soon off period. Time spent in hypoglycaemia below 2.8mmol/L was significantly different in the 24 hours after activity favouring the urgent low soon (p=0.035).REC name
London - Westminster Research Ethics Committee
REC reference
19/LO/1529
Date of REC Opinion
13 Nov 2019
REC opinion
Further Information Favourable Opinion