Oxidative Stress in Endometriosis
Research type
Research Study
Full title
OXidative Stress in women with Endometriosis pre and poSt Surgery (XSESS)
IRAS ID
246994
Contact name
Ying Cheong
Contact email
Sponsor organisation
Research and Development Department
Duration of Study in the UK
5 years, 0 months, 1 days
Research summary
Oxidative stress resulting in free radical tissue injury is a known consequence of endometriosis. One of the free radical mediated mechanisms of injury is that of damage to the oocytes (eggs) within the ovary, resulting in poorer reproductive outcomes, and possibly longer term detrimental impact on the babies born. It is not known if surgery, besides removing endometriotic lesions, also impacts on the levels of oxidative stress. We aim to investigate whether surgical treatment reduces oxidative stress in women with endometriosis. This research will increase our understanding of the wider beneficial impact of endometriosis surgery and provide a further mechanistic insight into free-radical tissue injury in the context of endometriosis.
REC name
North West - Greater Manchester West Research Ethics Committee
REC reference
18/NW/0509
Date of REC Opinion
17 Aug 2018
REC opinion
Further Information Favourable Opinion