Outcomes important to patients with Psoriatic Arthritis
Research type
Research Study
Full title
Identifying outcomes important to patients with Psoriatic Arthritis (PsA) and improving current outcome measurement tools
IRAS ID
185598
Contact name
Emma Dures
Contact email
Sponsor organisation
University of the West of England
Duration of Study in the UK
1 years, 0 months, 26 days
Research summary
This study is part of the PROMPT research programme to test whether early detection improves outcome in patients with undiagnosed psoriatic arthritis (PsA). PsA is an inflammatory arthritis which can cause pain, swelling and stiffness in the joints and may result in severe disability and reduced quality of life. The burden of undiagnosed PsA is high and there is evidence that delay in diagnosis results in worse outcome. Therefore, the principal PROMPT study will be a randomised controlled trial (RCT) to investigate the benefit of earlier diagnosis of psoriatic arthritis (PsA). Before the RCT can begin, it is important that the study includes patient reported outcomes (PROMs) that are meaningful from the patient perspective. The measures currently used in PsA trials have been developed largely by professionals, consequently we cannot know that they include what matters most to patients.
The aim of our study is to identify the outcomes that are important to patients and to compare them to the existing measures. If patients identify important outcomes that are not currently measured, the team will identify validated PROMS that capture these. This will serve two immediate purposes: to inform the outcomes included in the main RCT, and to prospectively test the performance of any new, additional measures in patients with newly diagnosed PsA (in a separate study PROMPT study). In the longer term, this project will lead to the development of a validated and practical set of measures capturing all relevant domains of the condition from the patient perspective that can be adapted to the needs of the research community, patients with PsA and the clinicians providing treatment and care.
REC name
North West - Haydock Research Ethics Committee
REC reference
15/NW/0609
Date of REC Opinion
22 Jul 2015
REC opinion
Further Information Favourable Opinion