Outcomes after TKR: a DCE
Research type
Research Study
Full title
What are the most important outcomes to patients after total knee replacement? A discrete choice experiment.
IRAS ID
339639
Contact name
Philippa Nicolson
Contact email
Sponsor organisation
Oxford University Hospitals NHS Foundation Trust
Duration of Study in the UK
0 years, 11 months, 28 days
Research summary
Total knee replacement surgery is recommended for people with knee osteoarthritis whose symptoms have not improved with other treatments. After someone has had a knee replacement we can measure their recovery in many ways, including how much they can move their knee, what the joint looks like on x-ray, how much pain they have, what activities they are able to do or whether the joint replacement needs further surgery. Currently we do not know which of these are most important to people who have had knee replacement surgery.
We aim to understand which measures of recovery people who have had a total knee replacement think are most important.
We have worked with people who have had knee replacement surgery to design a questionnaire which includes pairs of total knee replacement recovery scenarios. By asking people to repeatedly choose between the scenarios which have varying combinations of outcomes we can find out which measures of recovery are most important to them. At least 300 people who have had a total knee replacement will complete the questionnaire.
We will share our findings with healthcare professionals and patient groups, at conferences, through a short summary shared with professional networks, and through social media. Our findings will also be reviewed by academic peers and published in an academic journal.
REC name
North West - Greater Manchester Central Research Ethics Committee
REC reference
25/NW/0317
Date of REC Opinion
15 Oct 2025
REC opinion
Favourable Opinion