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Orofacial pain and quality of life - how are they linked?

  • Research type

    Research Study

  • Full title

    Emotional state as related to chronic orofacial pain and oral-health related quality of life

  • IRAS ID

    314812

  • Contact name

    Pauline Adair

  • Contact email

    p.adair@qub.ac.uk

  • Sponsor organisation

    Queen's University Belfast

  • Clinicaltrials.gov Identifier

    N/A, N/A

  • Duration of Study in the UK

    1 years, 1 months, 29 days

  • Research summary

    Chronic orofacial pain is regarded as pain that occurs in the head, face, and mouth area. Chronic orofacial pain and depression can co-occur, with higher levels of depression reported amongst individuals experiencing chronic orofacial pain compared to healthy controls. Quality of life is shown to be significantly impacted by chronic orofacial pain. The relationship between depression and associated variables of anxiety and stress, chronic orofacial pain, and oral health-related quality of life therefore seems an important area for exploration and may offer more specificity in outcome. Whether depression may mediate or moderate the relationship between chronic orofacial pain and oral health-related quality of life might allow for a deeper understanding of how these constructs interact with each other.

    The current study aims to understand the relationships between emotional state as captured by depression, anxiety, and stress, chronic orofacial pain, and oral health-related quality of life. This study aims to answer the following three main research hypotheses:

    1) Emotional state (depression, anxiety, and stress) will predict oral health-related quality of life in patients with chronic orofacial pain
    2) Emotional state (depression, anxiety and stress) will mediate the relationship between chronic orofacial pain and oral health-related quality of life
    3) Emotional state (depression, anxiety and stress) will moderate the relationship between chronic orofacial pain and oral health-related quality of life.

  • REC name

    Yorkshire & The Humber - Bradford Leeds Research Ethics Committee

  • REC reference

    22/YH/0193

  • Date of REC Opinion

    12 Aug 2022

  • REC opinion

    Further Information Favourable Opinion

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