ORL-PGI-2261
Research type
Research Study
Full title
A cosmetic study to assess plaque accumulation and changes to gingival health after four days of non-brushing and use of three novel toothpastes compared to a silica fluoride control toothpaste
IRAS ID
193850
Contact name
Iain Chapple
Contact email
Sponsor organisation
Unilever Research & Development
Duration of Study in the UK
0 years, 4 months, 29 days
Research summary
Plaque is a layer of bacteria that builds up on teeth and other surfaces in the mouth. It is believed that plaque can contribute to gingivitis (gum disease). Gingivitis in severe cases is known as periodontitis and is the most common cause of tooth loss. It is believed that antioxidants and nutrients may be useful in treating periodontitis. This study is testing three new toothpastes that contain antioxidants and vitamins. The objective of this study is to assess the effect the toothpastes have on the accumulation of plaque and the health of the gums. If these toothpastes are clinically effective, they may become a useful treatment for gum disease.
REC name
West Midlands - Coventry & Warwickshire Research Ethics Committee
REC reference
15/WM/0421
Date of REC Opinion
7 Dec 2015
REC opinion
Favourable Opinion