ORDIT

• Research type

  Research Study

• Full title

  Organ Dysfunction in Trauma: a national one month point prevalence study

• IRAS ID

  173441

• Contact name

  Karim Brohi

• Contact email

  k.brohi@qmul.ac.uk

• Sponsor organisation

  Queen Mary University of London

• Duration of Study in the UK

  1 years, 4 months, 1 days

• Research summary

  Traumatic injury is a leading cause of death. Severe injuries may be caused by incidents such as vehicle collisions, falls or assaults. People who survive the initial injuries may be admitted to an intensive care unit (sometimes called a ‘critical care’ unit). Whilst in this unit a proportion of patients will develop a problem with some of their vital organs (the heart, lungs, or liver, for example) where one or more organs do not function as they did prior to the trauma. This is known as multiple organ failure (MOF) and it is a problem because it prolongs the patients hospital stay, complicates their recovery and in some cases, causes late death.
  Trauma care in the UK has changed since the introduction of organised trauma systems in April 2010. Severely injured patients are now taken to specialist major trauma centres for expert management. Research in Australia and the USA suggests that this type of specialist care helps to reduce the incidence of MOF, but we do not know if this is the case for British trauma patients. However, the newly organised national trauma system is perfectly positioned to research MOF in the UK. This will improve our understanding of which types of patients develop MOF. This may help to prevent or reduce the incidence of MOF, and enhance the patients recovery and experience after their injuries.

• REC name

  London - South East Research Ethics Committee

• REC reference

  15/LO/1626

• Date of REC Opinion

  29 Oct 2015

• REC opinion

  Further Information Favourable Opinion