Optimising T cell reactivation to tumour antigens in vitro

  • Research type

    Research Study

  • Full title

    Optimising T cell reactivation to tumour antigens in vitro − studies on healthy volunteers

  • IRAS ID

    241778

  • Contact name

    Steven P Lee

  • Contact email

    s.p.lee@bham.ac.uk

  • Sponsor organisation

    University of Birmingham

  • Duration of Study in the UK

    1 years, 1 months, 31 days

  • Research summary

    We are seeking to develop an immune−based therapy for human cancer whereby patients are injected with large numbers of immune cells called T cells, that are capable of seeking out and destroying the tumour. Such T cells can be present in the bloodstream of cancer patients and healthy individuals but are rare and often difficult to grow in the laboratory. The current project, which will be carried out entirely in the laboratory, explores new methods to generate such cancer−specific T cells.

  • REC name

    East of England - Cambridgeshire and Hertfordshire Research Ethics Committee

  • REC reference

    18/EE/0273

  • Date of REC Opinion

    29 Aug 2018

  • REC opinion

    Further Information Favourable Opinion