OPTIMISE-HFpEF

• Research type

  Research Study

• Full title

  Optimising CMR Scan Acquisitions for novel equipment/sequences in Clinical Cardiovascular Populations (OPTMISE-HFpEF).

• IRAS ID

  314772

• Contact name

  Gerry McCann

• Contact email

  gpm12@le.ac.uk

• Sponsor organisation

  University of Leicester

• Duration of Study in the UK

  1 years, 0 months, 0 days

• Research summary

  Research Summary:
  Alternative methods to pharmacological stress cardiac magnetic resonance imaging (CMR) are required for diagnostic and prognostic information in patients with suspected and established heart failure. Exercise CMR (Ex-CMR) offers an alternative to pharmacological stress CMR, better replicating the neurohormonal and haemodynamic changes associated with physical exercise. Reproducible Ex-CMR protocols need to be developed in specific clinical cardiovascular populations. In this study we will develop reproducible Ex-CMR protocols in patients with established heart failure and preserved ejection fraction (HFpEF) and those at risk of or with early HFpEF.

  Summary of Results;
  Thirty participants were recruited and data collected. The image quality was poor.

• REC name

  West Midlands - South Birmingham Research Ethics Committee

• REC reference

  22/WM/0145

• Date of REC Opinion

  22 Jul 2022

• REC opinion

  Further Information Favourable Opinion