Optical Coherence Tomography Angiography NEtwork (OCTANE) Study
Research type
Research Study
Full title
Optical Coherence Tomography Angiography NEtwork (OCTANE) Study in chorioretinal diseases
IRAS ID
216798
Contact name
Jane Dennison
Contact email
Duration of Study in the UK
2 years, 0 months, 0 days
Research summary
OCT-Angiography (OCTA) is a new technology that is able to identify features detected using both OCT(optical Coherence Tomography) and FA (Fluorescein Angiography) providing more detailed resolution of retinal structural and flow characteristics, without the need for a dye injection. Such devices are just beginning to become available in some NHS Trusts in the UK because it is innovative, non-invasive, fast and has provided new insights into the pathogenesis of AMD and other retinal conditions. However, it’s use has not been validated in large, prospective clinical trials on the basis of high-volume data. There is therefore an unmet need to evaluate the diagnostic performance of OCT-A and compare it to the current standard imaging used to diagnose these conditions.
In addition, the normal patterns of the retina and choroid, as seen on OCT-A have not been published from large patient groups. This research will address the gap in knowledge on OCT-A and assess its performance as an imaging tool in the NHS. In addition, this research will provide information to update the current national retinal disease pathways incorporating robust and up-to-date imaging technology in order to effectively and cost-effectively accommodate the ever-increasing numbers of patients affected by this aggressive vision-threatening pathology.REC name
East Midlands - Leicester Central Research Ethics Committee
REC reference
16/EM/0469
Date of REC Opinion
7 Nov 2016
REC opinion
Favourable Opinion