Optical Biopsy Retargeting and Recognition for GI Endoscopy
Research type
Research Database
IRAS ID
179115
Contact name
Julian Teare
Contact email
Research summary
Gastrointestinal Endoscopy Database for Optical Biopsy Retargeting and Recognition
REC name
London - Chelsea Research Ethics Committee
REC reference
16/LO/0798
Date of REC Opinion
13 Jul 2016
REC opinion
Further Information Favourable Opinion
Data collection arrangements
Up to 1000 patients who are to undergo endoscopy for gastrointestinal disease visualisation or therapies may be recruited. The consultant or other member of the clinical team who is managing the patient care will perform the endoscopic examinations. The endoscopic images and videos will be acquired and recorded during the examination using recording systems. The positioning data of the endoscope, if available, will be stored along with the videos. The patient information will be hidden from the recorded data, and kept anonymous. It should be noted that all the data will be acquired during a routine procedure with no change in the standard clinical practice as far as the patient is concerned.
Research programme
Optical biopsy is a procedure that uses advanced imaging techniques, such as fibred confocal microscopy, optical coherence tomography and narrow band imaging, to perform real-time and in-vivo pathology examination. Compared to traditional biopsy that retrieves tissue sample for histopathology analysis, optical biopsy allows polyp differentiation to be performed on-the-fly during the procedure. In addition, optical biopsy also provides the benefit that reduces the cost burden related to the removal and pathology analysis of the tissue. The database will be used to develop and evaluate computer vision techniques for optical biopsy retargeting and recognition, which helps diagnosis of pathologies during GI endoscopy performed by gastroenterologists. Diagnosis with retargeting and recognition would help identifying precancerous areas along the GI tract of the patients. The research team is joined by clinicians who are expert gastroenterologists based in the GI units of Imperial College Healthcare NHS Trust, London and research engineers from the Hamlyn centre for robotic surgery based in Imperial College London. The clinicians will manage obtaining the patient consent and data recording, while the engineers will maintain the database and related server/IT issues.
Research database title
Gastrointestinal Endoscopy Database for Optical Biopsy Retargeting and Recognition
Establishment organisation
Imperial College London
Establishment organisation address
South Kensington Campus
London
United Kingdom
SW7 2AZ