Omega (n)-3 PUFA enriched beef & health outcomes
Research type
Research Study
Full title
Omega (n)-3 PUFA enriched beef to improve circulating lipid concentrations and CVD risk markers in adults: a randomised controlled study
IRAS ID
251073
Contact name
Ruth Price
Contact email
Sponsor organisation
Ulster University
Clinicaltrials.gov Identifier
FCBMS-18-152, School of Biomedical Sciences Ethics Filter Committee
Duration of Study in the UK
1 years, 3 months, 1 days
Research summary
Red meat is an integral component of the habitual diet among the UK and Irish population, with adults consuming an average of 71g/d. Although typically high in saturated fatty acids (SFA), red meat is also an important dietary source of protein and essential nutrients including iron, zinc, B vitamins and long chain n-3 polyunsaturated fatty acids (PUFA) which provide numerous benefits to human health, particularly related to cardiovascular disease (CVD) risk. N-3 and n-6 PUFA are a family of fatty acids with important roles in cardiovascular health, and it is often recommended in dietary guidelines to replace SFA with unsaturated fats, such as PUFA. Owing to the social and economic burden of CVD, increasing the proportions of these unsaturated fatty acids, in combination with a reduction in SFA within meat, could have a large impact on CVD risk at the population level, whilst retaining the beneficial nutrients and n-3 PUFA which meat provides.\n\nIn this research, a total of 90 eligible and consenting participants will be randomly allocated to consume three portions per week of n-3 enriched beef (from either dietary supplemented or grass-fed cattle) or control beef (from standard supply). This beef will be offered within a lunchtime meal and served from the Human Intervention Studies Unit at Ulster University, Coleraine for a period of 5 weeks.\n\nA fasting blood sample will be taken before and after intervention to determine the effect the n-3 enriched beef on cholesterol concentrations, lipid profile, PUFA status and inflammation. Blood pressure, stiffness of the arteries and body shape, size and composition will also be assessed, and some health and lifestyle habits will be captured using questionnaires. An honorarium of £50 will be paid to all participants upon completion of the study to cover their time and travel costs throughout the 5-week study.
REC name
West of Scotland REC 5
REC reference
18/WS/0149
Date of REC Opinion
3 Oct 2018
REC opinion
Further Information Favourable Opinion