Omega

  • Research type

    Research Study

  • Full title

    Prospective, Single-arm Study to Assess the Safety and Performance of the Omega™ Left Atrial Appendage (LAA) Occluder in Patients with Non-Valvular Atrial Fibrillation and High Bleeding Risk

  • IRAS ID

    293866

  • Contact name

    David Hildick-Smith

  • Contact email

    david.hildick-smith@nhs.net

  • Sponsor organisation

    Eclipse Medical Ltd.

  • Clinicaltrials.gov Identifier

    NCT04829929

  • Duration of Study in the UK

    2 years, 5 months, 18 days

  • Research summary

    Clinical study to assess the Omega™ Left Atrial Appendage (LAA) Occluder in Patients with atrial fibrillation and high bleeding risk. \n\nThe clinical trial OMEGA is a multicenter study assessing the OMEGA™ LAA (Left Atrial Appendage) Occluder in patients suffering from atrial fibrillation for which usual anticoagulant medications are considered to be not completely safe due to high risk of bleeding. The OMEGA™ device will potentially reduce the risk of blood clot formation in the left atrial appendage and reduce the risk of stroke. \n \n100 patients will participate in this study at up to 10 sites in Europe. Participation in this study is expected to take approximately 24 months in total for each patient and includes four follow up visits. \n \nThe risks of participation in this study is similar to the risk of treatment with other comparable devices (LAA Occluder). \n \nThe Sponsor of the study – Eclipse Medical Ltd. – is paying for conducting the study.

  • REC name

    North of Scotland Research Ethics Committee 1

  • REC reference

    21/NS/0121

  • Date of REC Opinion

    28 Oct 2021

  • REC opinion

    Further Information Favourable Opinion