Olympus Lucera vs Olympus Elite - an observational study
Research type
Research Study
Full title
A prospective study comparing the accuracy of Olympus Lucera Spectrum technology vs Olympus Lucera Elite technology in the in vivo diagnosis of Barrett’s oesophagus and colorectal polyps: The ELITE Study.
IRAS ID
192502
Contact name
Fergus Chedgy
Contact email
Sponsor organisation
Portsmouth Hospitals NHS Trust
Duration of Study in the UK
1 years, 6 months, 0 days
Research summary
Barrett’s oesophagus is a condition where the lining of the oesophagus (gullet) wall changes. People with Barrett’s oesophagus are at risk of developing oesophageal cancer but can have regular check-ups to detect changes before they progress to cancer. Every two years patients with Barrett's are offered examination by passing a fibre-optic tube into the oesophagus (gastroscopy) to remove small tissue samples (biopsies), which are examined in the laboratory to check for changes.
Bowel cancer is the third most common cancer in the UK, and the second leading cause of cancer deaths. Prevention and early detection are the most effective strategies of dealing with bowel cancer. Most cancers develop from benign polyps (growths) in the bowel. Polyps are common and have the potential of developing into cancer over the course of many years.
Patients with a prior diagnosis of Barrett’s oesophagus and colonic polyps undergo regular endoscopic examinations known as surveillance endoscopies. This is done to detect changes in the cells of Barrett’s oesophagus or further polyps. Our current practice is to capture recorded videos of Barrett’s surveillance examinations and still images of polyps prior to their removal.
Endoscope technology continues to advance. These newly developed technologies are marketed to have claims of superiority in performance over preceding generations often without the back up of scientific data but at a significant financial cost. The aim of this study is to use endoscopic images and videos recorded as part of routine clinical practice to compare the current version of Olympus endoscopes with the new version launched by the company.REC name
North East - Tyne & Wear South Research Ethics Committee
REC reference
15/NE/0387
Date of REC Opinion
12 Nov 2015
REC opinion
Favourable Opinion