Oedema Management with geko following Foot and Ankle Surgery

  • Research type

    Research Study

  • Full title

    Postoperative Oedema Management of Foot and Ankle Patients with Neuromuscular Electro-stimulation of the Peroneal Nerve using geko™

  • IRAS ID

    300770

  • Contact name

    Shelain Patel

  • Contact email

    shelain.patel@nhs.net

  • Sponsor organisation

    Firstkind Ltd

  • Clinicaltrials.gov Identifier

    NCT04927234

  • Duration of Study in the UK

    1 years, 6 months, 1 days

  • Research summary

    Summary of Research

    Having some leg swelling is a normal part of the healing process following foot or ankle surgery. This swelling is often caused by a build-up of fluid in the area where surgery has taken place and is called oedema. Oedema can be painful and slow down patient recovery post surgery. The standard care patients receive from hospital after surgery consists of treatments used within the NHS to help prevent and reduce oedema formation and aid recovery e.g. keeping leg raised Another treatment which may also help to prevent and reduce oedema formation after foot and ankle surgery is treatment with a medical device called the geko™ device. The geko™ device is a CE marked medical device which means the manufacturer has checked that the device complies with the essential safety and performance requirements for its’ intended use which is to increase blood circulation and prevent and treat oedema. Following the consent process patients who have had foot and or ankle surgery will receive one of two treatments, either standard or standard care with the addition of treatment with the geko™ device for 12 hours / day for approximately 14 days. There will be 3 follow-up visits which will take place round about 2 weeks, 6 weeks and 12 weeks post-surgery.
    The primary objective of the study is to assess oedema formation with and without geko™ therapy on patient outcomes during the follow-up period of up to three months post-surgery to identify which treatment will provide the best clinical outcome for patients

    Summary of Results

    This study evaluated the addition of the geko® muscle-stimulating device to standard postoperative
    care following forefoot and/or hindfoot surgery Objectives To determine whether using the geko®
    care following forefoot and/or hindfoot surgery. Objectives To determine whether using the geko®
    device alongside standard care reduces postoperative swelling (oedema) more effectively than standard
    care alone. To assess whether the device supports faster wound healing. To confirm the safety and
    tolerability of the geko® device in this patient population. Methods Swelling measurement: We
    compared the circumference of the operated leg with the non-operated leg to calculate an oedema
    ratio. Wound healing assessment: We recorded the number of patients whose surgical wounds were
    fully healed by 14 days after surgery. Leg recovery measurement: We used a “figure-of-eight” (Fo8)
    tape measurement around the foot and ankle to assess restoration toward pre-surgery size. Safety and
    patient comfort: We monitored adverse events (AEs) and collected patient-reported pain scores (Visual
    Analogue Scale, VAS) and foot-function questionnaires (Manchester Oxford Foot Questionnaire,
    MOxFQ). Key Findings Significant reduction in swelling At 14 days post-surgery, the oedema ratio was
    significantly lower in the group receiving geko® plus standard care versus standard care alone. The
    strongest statistical significance was observed in the Spanish cohort (p = 0.007), with a consistent trend
    when combining data from Spain and the UK (p = 0.02). Improved leg circumference recovery The
    percentage increase in Fo8 measurement from baseline to Day 14 was significantly less in the geko®
    group, indicating more rapid return to normal leg size. Enhanced wound healing A higher proportion of
    wounds were fully healed, and fewer wounds exhibited delayed healing in the geko® group compared
    to standard care only. Sub-analysis of patients undergoing bunion (hallux valgus) surgery confirmed a
    significant reduction in swelling with geko® use (p < 0.05). Safety and tolerability No device-related
    safety concerns or serious adverse events were reported. Pain scores (VAS) and patient-reported foot
    function (MOxFQ) were similar between both groups, indicating that the geko® device did not
    introduce any additional discomfort. Conclusion The addition of the geko® muscle-stimulating device
    to standard postoperative care demonstrates clear benefits in reducing swelling, promoting faster
    wound healing, and supporting overall recovery after forefoot and/or hindfoot surgery. The device was
    well tolerated, with no new safety issues identified. These results endorse the geko® device as a
    valuable adjunct therapy in this clinical setting.

  • REC name

    West of Scotland REC 4

  • REC reference

    21/WS/0099

  • Date of REC Opinion

    5 Nov 2021

  • REC opinion

    Further Information Favourable Opinion