OCTOBER study (v3.0)

  • Research type

    Research Study

  • Full title

    Nordic-Baltic-British Study on Optical Coherence Tomography Optimized Bifurcation Event Reduction

  • IRAS ID

    230772

  • Contact name

    Simon J Walsh

  • Contact email

    simon.walsh@belfasttrust.hscni.net

  • Sponsor organisation

    Aarhus University Hospital

  • Clinicaltrials.gov Identifier

    NCT03171311

  • Duration of Study in the UK

    15 years, 0 months, 1 days

  • Research summary

    Patients with ischaemic heart disease and narrowed coronary arteries often have a pattern of coronary disease that involves a branch point or bifurcation (like a fork-in-the-road). When these patients are treated by angioplasty or stenting procedures (often called percutaneous coronary intervention or PCI), the best method of managing these specific bifurcation lesions is still in doubt. Modern coronary stents (wire mesh scaffolds that hold the coronary artery open) can now be implanted by a number of different techniques to manage bifurcation lesions. However, the optimal method of achieving the best outcome for a specific patient is still a matter of debate. This study will examine if supplementing usual care, where PCI is guided by X-ray only, could potentially be enhanced by adding imaging from inside the coronary artery with optimal coherence tomography (OCT; light based imaging to provide very detailed images).

  • REC name

    HSC REC A

  • REC reference

    17/NI/0204

  • Date of REC Opinion

    7 Nov 2017

  • REC opinion

    Favourable Opinion