Obstructive sleep apnoea and autonomic neuropathy in type 1 diabetes

• Research type

  Research Study

• Full title

  Obstructive sleep apnoea and autonomic neuropathy in adults with type 1 diabetes; an observational study

• IRAS ID

  160021

• Contact name

  Alex Astor

• Contact email

  sponsor@liv.ac.uk

• Duration of Study in the UK

  0 years, 4 months, 1 days

• Research summary

  To determine the prevalence of obstructive sleep apnoea (OSA) and autonomic neuropathy in people with type 1 diabetes at University Hospital Aintree.
  Current research has shown strong links between OSA and obesity/type 2 diabetes. However, a few limited studies have suggested a higher than expected prevalence of OSA in lean individuals with type 1 diabetes.
  Patients with type 1 diabetes will be recruited and investigated for:
  1) autonomic neuropathy - using an ECG machine to record variations in electrical activity of the heart in response to standing, deep breathing and valsalva manoeuvre and also by measuring blood pressure response to standing and sustained handgrip
  2) OSA – using a portable polysomnographic device which can be used at the participants home to record the individuals apnoea hypopnea index over one night
  

• REC name

  Yorkshire & The Humber - South Yorkshire Research Ethics Committee

• REC reference

  14/YH/1231

• Date of REC Opinion

  4 Dec 2014

• REC opinion

  Further Information Favourable Opinion