Objective Assessment of Scleroderma skIn tissueS (OASIS)
Research type
Research Study
Full title
Objective Assessment of Scleroderma skIn tissueS (OASIS)
IRAS ID
306077
Contact name
Peter Worsley
Contact email
Sponsor organisation
University of Southampton
Clinicaltrials.gov Identifier
IRAS Project ID: 306077 ERGO-67865,
Duration of Study in the UK
0 years, 6 months, 24 days
Research summary
Scleroderma is an extremely variable and rare disease which can affect the skin and internal organs. For some patients severe disability and death can occur within three years of diagnosis but for others it can remain completely benign. We are currently unable to predict the course of the disease and all patients are extensively screened in specialist rheumatology clinics every six months. often these changes can starts as circulation problem where fingers and toes turn white in the cold. other typical symptoms include thickening of the skin over the hands, feet and face, red spots on the skin, hard lumps under the skin, heartburn and problems swallowing (dysphagia) This study aims to achieve the following 1. Establish the feasibility of using non-invasive skin measurement tools in a cohort of scleroderma patients.2. Compare the skin parameters derived from the measurement tools with those routinely collected in clinical practice e.g., Modified rodnan Scale.
REC name
HSC REC B
REC reference
22/NI/0049
Date of REC Opinion
18 Mar 2022
REC opinion
Further Information Favourable Opinion