Nutrileads H03
Research type
Research Study
Full title
Efficacy and tolerability of NL-01, a food ingredient, in older adults (≥65 y) at risk of URTI infections during the winter season.
IRAS ID
247195
Contact name
Gordon Crawford
Contact email
Sponsor organisation
Nutrileads
Duration of Study in the UK
0 years, 9 months, 29 days
Research summary
The aim of this study is to test NL-01 in older adults, at risk of respiratory tract infection, to determine if daily dietary supplementation with NL-01 reduces the incidence, duration or severity of URTI in the winter season. Globally, acute respiratory tract infections are the most common of all illnesses; they are generally caused by rhinovirus, adenovirus, coronavirus, and influenza. Influenza is associated with the most severe respiratory viral illness (RVI), but rhinoviruses—which manifest as the common cold—cause the greatest number of respiratory viral illness. Frequently these respiratory tract infections are followed by a secondary infection that can lead to pulmonary infections, like pneumonia. Individuals that are ≥ 65 years have increased risk to airway infections especially those who have lower immunity, impaired function which impacts daily living, co-morbidities (other diseases), or a suppressed immune response. These conditions are frequently associated with borderline nutrition status. Every year, during the cold season, health care professionals need to spend much of their time on the diagnosis and treatment of elderly subjects with respiratory infections. Significant reduction of the number or duration of URTI episodes would be of great benefit for subjects with increased risk of respiratory tract infections and for the health care system as a whole.
REC name
East of Scotland Research Ethics Service REC 2
REC reference
18/ES/0069
Date of REC Opinion
28 Jun 2018
REC opinion
Further Information Favourable Opinion