Nucleoli morphokinetics using time-lapse imaging v1
Research type
Research Study
Full title
An assessment of the effect of nucleoli morphokinetics using a time-lapse imaging system on human embryo quality and subsequent pregnancy.
IRAS ID
201137
Contact name
Clare F Giraud (nee Clubbs)
Contact email
Sponsor organisation
The Shrewsbury and Telford Hospital NHS Trust
Duration of Study in the UK
0 years, 10 months, 30 days
Research summary
Does nucleoli pattern and timing predict embryo quality and subsequent pregnancy outcome?
Embryo selection is one of the major obstacles in assisted reproductive techniques (ART). Selecting the embryo with the highest potential to result in a healthy baby currently relies upon static observations of embryo appearance. Time-lapse imaging systems (TLS) allow us to view the development of embryos as a continuous 'video'. Specific structures seen during early development (nucleoli) using TLS may offer important information to help aid the selection of the best embryo. This project seeks to investigate nucleoli development and its importance in selecting the best embryos in order to increase pregnancy and birth rates.
REC name
West of Scotland REC 3
REC reference
16/WS/0079
Date of REC Opinion
15 Apr 2016
REC opinion
Favourable Opinion