Novel technologies for diagnosing and monitoring pulmonary diseases

  • Research type

    Research Study

  • Full title

    The application of novel technologies to identify new biomarkers for diagnosing and monitoring pulmonary diseases.

  • IRAS ID

    187325

  • Contact name

    Keir Lewis

  • Contact email

    keir.lewis@wales.nhs.uk

  • Duration of Study in the UK

    10 years, 0 months, 0 days

  • Research summary

    We hope to use new gene and protein technologies currently only available in Universities, to measure combinations of the most promising molecules and microbes(biomarkers) from sputum, blood, saliva, urine, pleural fluid and any biopsy samples from people attending hospital with lung diseases and compare them with samples from people with other lung diseases and healthy controls. Testing on samples which are more easily and safely obtained than deep biopsies and then applying newer cutting edge technologies we hope we can better detect and monitor lung cancer and Chronic Obstructive Pulmonary Disease (COPD). We will also apply special ways of measuring and combinations of biomarkers rather than a single reading. The work applies high-throughput, automated so rapid and potentially more accurate and cost-effective detection “omics” technologies.

  • REC name

    Wales REC 7

  • REC reference

    16/WA/0036

  • Date of REC Opinion

    2 Feb 2016

  • REC opinion

    Favourable Opinion