novel dialyzer
Research type
Research Study
Full title
Pilot study to develop a novel dialyzer to remove toxins from kidney failure patients
IRAS ID
258192
Contact name
Andrew Davenport
Contact email
Sponsor organisation
University College London
Clinicaltrials.gov Identifier
No Z6364106/2019/02/40, UCL Data Protection Registration
Duration of Study in the UK
1 years, 7 months, 31 days
Research summary
The kidneys clear waste products from the body. In kidney failure these waste products accumulate and cause harm. Kidney dialysis treatments are very good at clearing small water soluble waste products.
Kidney failure patients have increased risk of dying, and survival is less than that for bowel cancer. Kidney dialysis treatments are not good at removing waste products (toxins) attached to proteins. These toxins have been shown in cell culture experiments, animal experiments to cause damage to the heart and blood vessels. In observational studies in patients, kidney failure patients with higher levels of these toxins have worse survival.
We wish to develop a new type of kidney dialyzer that can remove these toxinsREC name
HSC REC A
REC reference
19/NI/0083
Date of REC Opinion
11 Apr 2019
REC opinion
Further Information Favourable Opinion