Nottingham Adult Brain Tumour Bank

• Research type

  Research Tissue Bank

• IRAS ID

  357723

• Research summary

  Nottingham Adult Brain Tumour Bank

• REC name

  East Midlands - Derby Research Ethics Committee

• REC reference

  25/EM/0160

• Date of REC Opinion

  12 Aug 2025

• REC opinion

  Favourable Opinion

• Data collection arrangements

  People undergoing surgery for brain tumours in the East Midlands will be approached and the opportunity for donating samples to the biobank discussed before their operation. We will collect and store samples of brain tumours where there is excess material removed as part of their standard clinical care above what is needed for the NHS diagnostic process. Samples of excess material will be stored in the Biodiscovery Institute under the auspices of the University of Nottingham, in an anonymised and secure fashion. Non-identifiable data will be stored such as age and biological sex of the person undergoing surgery. No extra tests, clinical visits or other input will be required from the person undergoing surgery or their next of kin. People will be given time to consider their participation before their operation and will be free to withdraw consent at any time. Their decision to participate or not to participate will have no bearing or impact on their clinical care either way.

• Research programme

  There is a highly active and expanding brain tumour research programme at the University of Nottingham studying many aspects of brain tumours in adults. Brain tumours are a highly variable and diverse group of tumours with many different subtypes. A biobank that is able to support the diversity of potential projects in multiple different tumour types will be a highly valuable resource to support many projects looking at the causes of, the treatment and the prevention of brain tumours in their many different forms, as the specific answers will likely vary between different tumour types. Analysis undertaken will study the DNA, RNA and proteins within tumours as this is where they differ from normal tissues and the answers to how to improve care must lie. Laboratory research groups across the University of Nottingham will benefit from access to the tumour material in primary brain tumours and for cancers that spread to the brain such as melanoma, lung cancer and breast cancer.

• Storage license

  12265

• RTBTitle

  Nottingham Adult Brain Tumour Bank

• Establishment organisation

  University of Nottingham

• Establishment organisation address

  University of Nottingham, Research and Innovation, E-floor, Yang Fujia Building, Jubilee campus

  Nottingham

  NG8 1BB