Estimation of cardiac preload in acute care using non-invasive monitoring
University of Leicester
Duration of Study in the UK
1 years, 6 months, 30 days
This study will use a non-invasive monitoring device to look at the basic science of cardiac changes following a “passive leg raising test” (which increases the amount of blood coming into the heart). This device is like a normal heart tracing with sticky patches on the chest attached to wires.
Our aim is to see if we can identify the group of patients who will benefit from intravenous fluid resuscitation by studying the relationship between a passive leg raising test and the response to intravenous fluid.
This study will be carried out on patients who are having urgent intravenous fluids. First the monitoring system will be applied and patients will sit on their trolley for up to 3 minutes followed by a maximum of 3 minutes lying down with legs elevated. After the next 500mls of fluid have been infused this test will be repeated. It will then be repeated a second time after about 2000mls of fluids have been infused. Monitoring will be continued until the treating physician decides no more fluid resuscitation is needed (maximum of 8 hours).
East of England - Essex Research Ethics Committee
Date of REC Opinion
20 Jun 2016
Further Information Favourable Opinion