Non invasive cardiac output monitoring to reduce complication in NOF

• Research type

  Research Study

• Full title

  Non invasive cardiac output monitoring to guide goal directed fluid therapy in high risk patients undergoing urgent surgical repair of proximal femoral fractures.

• IRAS ID

  140209

• Contact name

  Simon Davies

• Contact email

  simon.davies@york.nhs.uk

• Sponsor organisation

  York Hospitals NHS Foundation Trust

• Research summary

  Many elderly people in the United Kingdom unfortunately break their hip ( fractured neck of femur) at some point in their lives. This is a growing problem and by 2033 it is some 100 000 people per year will require an operation in order to fix a broken hip. This has significant implications for the patient, as up to 60% will develop a complication whilst in hospital, and also to the NHS with projected costs of treating these patients of up to £2.7 billon.
  Research has shown that optimizing the amount of fluid that a patient receives whilst having major surgery such as having their broken hip fixed reduces post operative complications.. Despite this fluid optimization is rarely performed in patients with broken hips. One of the reasons that the technology required to do this has been quite invasive in that it is either inserted into the gullet, or requires a drip place into an artery, and hence is not tolerated by many patients. Newer technology that simple sits in the finger is available that will allow fluid optimisation in this group (Clearsight).

  Aims
  The aim of this study is to investigate whether optimising intraoperative fluid in high-risk patients having their broken hips fixed reduces complication

  This is a trial of patients undergoing surgical repair of a broken hip. We will use the Clearsight to measure stroke volume (how much blood the heart pumps in a single beat) and give fluid in order to maximize this . The control group will receive ‘conventional care’. We will measure common complication during the hospital admission such as a urinary infection through to more major complications such as a stroke or heart attack.

  Expected outcomes.

  We expect that the fluid optimisation will be easy to achieve in this group, and that it will reduce post operative complication rates.

  Implications.
  If the intervention is found to be successful it will reduce the amount of complications that patients suffer, and also the cost to the healthcare
  

• REC name

  Yorkshire & The Humber - Leeds West Research Ethics Committee

• REC reference

  14/YH/1170

• Date of REC Opinion

  22 Oct 2014

• REC opinion

  Further Information Favourable Opinion