Non-communicable disease and pregnancy outcomes

• Research type

  Research Study

• Full title

  The use of routinely collected maternity data at Imperial College Healthcare NHS Trust to assess quality of care and pregnancy outcomes for non-communicable disease in pregnancy.

• IRAS ID

  266404

• Contact name

  Edward Mullins

• Contact email

  edward.mullins1@nhs.net

• Sponsor organisation

  Imperial College London

• Duration of Study in the UK

  0 years, 6 months, 28 days

• Research summary

  The use of routinely collected maternity data at Imperial College Healthcare NHS Trust to assess quality of care and pregnancy outcomes for non-communicable disease (e.g. high blood pressure, diabetes) in pregnancy.

  This study will use routinely collected patient information (e.g. age, height, weight), stored on the Cerner electronic patient record, at Imperial College Healthcare NHS trust to assess our local data specifically for;
  1. Pregnancy outcomes
  -is there an association between first trimester blood pressure and birthweight (adjusted for gestation)?
  -is there an association between diabetes screening results and birthweight (adjusted for gestation)?
  -what is the incidence of hypertension in pregnancy?
  -what is the incidence of gestational diabetes?
  2. Quality of maternity care
  -have NICE guidelines have been followed in the prevention of hypertension in pregnancy?
  -have NICE guidelines been followed in the screening and management of gestational diabetes?
  Data from the electronic patient record will be summarised and anonymised by clinical analysts who are part of the extended direct care team.

  Analysis will use the SPSS statistics package and will be presented within the trust, published nationally and the anonymised dataset will be available for use by other, ethically approved research projects.

  Abstract Background London has the lowest smoking prevalence among pregnant women in England. However, it was unclear whether the low overall prevalence masked inequalities. This study investigated the prevalence of smoking among pregnant women in North West London stratified by ethnicity and deprivation.

  Methods
  Data regarding smoking status, ethnicity and deprivation were extracted from electronic health records collected by maternity services at Imperial Healthcare NHS Trust between January 2020 and August 2022.

  Results
  A total of 25 231 women were included in this study. At the time of booking of antenatal care (mean of 12 weeks), 4% of women were current smokers, 17% were ex-smokers and 78% never smokers. There were marked differences in the smoking prevalence between ethnic groups. Women of Mixed—White and Black Caribbean ethnicity and White Irish women had the highest prevalence of smoking (12 and 9%, respec

  tively). There was an over 4-fold increase in the prevalence of smoking between the most and the least deprived groups (5.6 versus 1.3%).

  Conclusions
  Even in a population with an overall low prevalence of smoking in pregnancy, women experiencing deprivation and from certain ethnic backgrounds have a high smoking prevalence and hence are the most likely to benefit from smoking cessation interventions.

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• REC name

  Yorkshire & The Humber - South Yorkshire Research Ethics Committee

• REC reference

  19/YH/0435

• Date of REC Opinion

  11 Dec 2019

• REC opinion

  Favourable Opinion