NODS
Research type
Research Study
Full title
Neuropsychiatric Outcomes and Disrupted Sleep following acquired brain injury
IRAS ID
343176
Contact name
Melanie Fleming
Contact email
Sponsor organisation
University of Oxford Research Governance, Ethics and Assurance
Duration of Study in the UK
2 years, 1 months, 30 days
Research summary
The two most common causes of brain injury are stroke and trauma. Both sleep and mental health problems are common after brain injury; we will investigate whether there is a relationship between poor sleep quality and worse mental health in this group. We will follow patients up, at approximately three-monthly intervals until one year after injury, to see how sleep and mental health symptoms change over time and with recovery.
We will assess sleep in detail using questionnaires, a sleep monitor worn on the wrist, a portable brain activity sensor, and a sleep mat. We will assess mental health (neuropsychiatric) symptoms using questionnaires. Participants will be asked to complete these assessments at baseline and at approximately 3 monthly intervals until they reach 12 months post-injury.
This data will allow us to explore the types of sleep disruption seen after brain injury and examine the association between sleep quality and mental health symptoms.
REC name
North West - Liverpool Central Research Ethics Committee
REC reference
25/NW/0248
Date of REC Opinion
24 Sep 2025
REC opinion
Further Information Favourable Opinion