NIS Amyloidosis Study RWE - EMN23/54767414AMY0001

  • Research type

    Research Study

  • Full title

    A Retrospective Observational Multicenter Study on the Management and Outcome of Patients with Systemic AL Amyloidosis in Europe

  • IRAS ID

    261554

  • Contact name

    Ashutosh Wechalekar

  • Contact email

    a.wechalekar@ucl.ac.uk

  • Sponsor organisation

    Stichting European Myeloma Network (EMN)

  • Duration of Study in the UK

    1 years, 0 months, days

  • Research summary

    This study aims to record data from a representative sample of patients in Europe diagnosed with AL-Amyloidosis with symptomatic organ involvement who have received at least one line of treatment.

    AL-Amyloidosis is a rare acquired disorder of a specific type of immune cells called plasma cells and is characterised by the formation and deposition of abnormal proteins (amyloid). These abnormal proteins are produced by plasma cells and their tissue deposition gradually results in organ damage and subsequently organ failure.

    The present study aims to define the standard of care in the treatment of patients diagnosed with AL-Amyloidosis and symptomatic organ involvement in Europe. The evidence generated from this study will serve as a compass to guide and focus on the identification of unmet medical needs for AL-Amyloidosis.

  • REC name

    London - Central Research Ethics Committee

  • REC reference

    19/LO/1419

  • Date of REC Opinion

    3 Oct 2019

  • REC opinion

    Favourable Opinion