Nimic Study
Research type
Research Study
Full title
Near Infrared Monitoring for Ischaemic Injury in Children with Congenital Cardiac Conditions.
IRAS ID
206916
Contact name
Jean Watson
Contact email
Sponsor organisation
NHS Greater Glasgow & Clyde
Duration of Study in the UK
0 years, 4 months, 31 days
Research summary
Near Infrared Monitoring for Ischaemic Injury in Children with Cardiac Conditions (NIMIC Study)
Children who have congenital cardiac conditions and undergo surgery can develop problems with their kidneys and bowel whilst in intensive care. In most cases these problems resolve but in severe cases can lead to a complications know as ‘Acute Kidney Injury’ (AKI) or ‘necrotising enterocolitis’ (NEC) in which the work of the kidneys may need to be done by a machine and the child unable to be fed into their stomach but directly into their blood stream. Unfortunately, the exact cause of AKI and NEC is unknown but, it is thought to be linked to the blood supply to the kidney and bowel being reduced due to the problems with the heart.
The purpose of this study is for us to investigate the use of fairly new type of monitoring called Near Infrared Spectroscopy (NIRS) which may be able to detect early signs of reduced blood flow to the kidneys and bowel using sticky patches containing light sensors placed on the infant's abdomen and back for the initial 48 hours after surgery whilst in intensive care.
Parents of children less than six months of age undergoing cardiac surgery at a single paediatric cardiac tertiary hospital will be invited to participate in the study over a 3-4 month recruitment period.
REC name
West of Scotland REC 4
REC reference
16/WS/0134
Date of REC Opinion
12 Jul 2016
REC opinion
Favourable Opinion