NIHR BioResource Centre Newcastle and NIHR BioResource V5
Research type
Research Study
Full title
NIHR BioResource Centre Newcastle and NIHR BioResource (Part of NIHR BioResource for Translational Research in Common and Rare Diseases)
IRAS ID
242599
Contact name
Christopher Morris
Contact email
Sponsor organisation
Newcastle upon Tyne Hospitals NHS Foundation Trust
Duration of Study in the UK
3 years, 11 months, 31 days
Research summary
NIHR BioResource Centre Newcastle will build on the existing NIHR BioResource Centre Cambridge and will form part of the National NIHR BioResource. The NIHR BioResource for Translational Research in Common and Rare Diseases is a collaboration between thirteen Biomedical Research Centres and/or Clinical Research Facilities, namely Cambridge, Newcastle, Manchester, Leeds, Maudsley, Leicester, Exeter, Southampton, Birmingham, Moorfields, Barts, University College London Hospitals and Guy’s and St Thomas’/King’s College London. This collaboration aims to establish a federated database of healthy individuals and patients with neurological, cardiovascular, infectious/inflammatory or immune disorders or rare diseases who are consented for recall for research (centrally and locally) on the basis of genotype or phenotype. The aim of the NIHR BioResource is to build on and integrate existing resources to promote recruitment of well genotyped and phenotyped participants into local and national studies coordinated through existing clinics within NIHR Biomedical Research Centres and/or Clinical Research Facilities.
The NIHR BioResource Centre Newcastle will contribute to this national endeavour through local recruitment of patients and volunteers from hospitals, GP surgeries and local recruitment initiatives. The NIHR BioResource Centre Newcastle will collect and store blood samples and derivatives including DNA from the individuals. For participants recruited via GP surgeries, or where the collection of a blood sample is not feasible, or where a participant is not willing to donate a blood sample, saliva samples may be taken and stored. Newcastle will establish a sampling frame from which people - with and without health problems - can be selected on the basis of their genotype and or phenotype, to be invited for observational studies or clinical trials referred to as Stage 2 research activity.
REC name
North East - Newcastle & North Tyneside 2 Research Ethics Committee
REC reference
18/NE/0138
Date of REC Opinion
22 Jun 2018
REC opinion
Further Information Favourable Opinion