Newcastle Uteroplacental Tissue Bank

• Research type

  Research Tissue Bank

• IRAS ID

  62844

• Research summary

  Newcastle Uteroplacental Tissue Bank

• REC name

  North East - Newcastle & North Tyneside 1 Research Ethics Committee

• REC reference

  16/NE/0167

• Date of REC Opinion

  18 Aug 2016

• REC opinion

  Further Information Favourable Opinion

• Data collection arrangements

  The main Tissue Bank storage site is on 3rd floor, William Leech Building, Newcastle University. A satellite freezer is located in the basement at the International Centre for Life.
  Anonymised clinical data will be stored on a secure computer database, linked via a study number to the original data collection sheet which will be kept in a separate location in a locked filing cabinet in a secure room. Copies of the signed patient consent form will be kept in the appropriate study site file within the NHS Trust Reproductive Health & Childbirth Research Team (RHCRT). Consent will be taken by a research nurse/midwife from the RHCRT or clinical member of the research team. These individuals will be available to answer any questions about participation.
  All women will be given the relevant Patient Information Sheet (PIS) and have time to consider this (minimum of 2 hours) prior to seeking written consent.
  An information sheet outlining the areas of investigation undertaken by the research group is sent to all women with their pregnancy booking information. This contains a contact number for further information and signposts online information sources.

• Research programme

  The Reproductive and Vascular Biology Group has an international reputation for high quality science projects and collaborations. The group's research focus is understanding the molecular mechanisms underlying cellular remodelling in the uterus and placenta. Disruption of these processes leads to clinical conditions such as preeclampsia, preterm labour, recurrent miscarriage, infertility and fetal growth restriction. These conditions are important and common causes of maternal and neonatal morbidity and mortality. Clinical data collected from patients will enable laboratory findings to be interpreted with appropriate clinical consideration. The tissue bank would be publicised on the departmental website and be made available to investigators within the Institute of Cellular Medicine for collaborative projects. Samples will only be released following peer review of proposed projects.

• Storage license

  12534

• RTBTitle

  Newcastle Uteroplacental Tissue Bank

• Establishment organisation

  Institute of Cellular Medicine, Newcastle University

• Establishment organisation address

  3rd Floor Leech Building

  Newcastle University

  NE2 4HH