Newcastle NIHR BioResource
Research type
Research Study
Full title
Newcastle NIHR BioResource
IRAS ID
158018
Contact name
Emma Raine
Contact email
Sponsor organisation
Newcastle upon Tyne NHS Foundation Trust
Duration of Study in the UK
2 years, 4 months, 31 days
Research summary
The NCL BioResource will build on the existing Cambridge BioResource and will form part of the National NIHR BioResource. The NIHR BioResource is collaboration between seven Biomedical Research Centres (UCL, Imperial, Kings/IoP, Oxford, Cambridge, Guys and St Thomas and South London and Maudsley) and one Biomedical Research Unit (Leicester) to establish a federated database of healthy individuals and patients with neurological, cardiovascular, or infectious/inflammatory or immune disorders or with rare diseases, who are consented for recall for research on the basis of genotype or phenotype. The aim of the NIHR BioResource is to build on and integrate existing resources to promote recruitment of well genotyped and phenotyped participants into local studies coordinated through existing clinics within NIHR Biomedical Research Units and Centres.
The NCL BioResource will contribute to this national endeavour through local recruitment of up to 10,000 patients and volunteers from local cohorts and affiliated hospitals. The NCL BioResource will collect and store blood samples and derivatives including DNA from the 10,000 individuals, where a participant is not willing to donate a blood sample, saliva samples may be taken and stored. NCL will focus on patient recruitment - and with the other BioResources - will establish a sampling frame from which people, with and without health problems, can be selected on the basis of their genotype and or phenotype to be invited for observational studies or clinical trials referred to as stage 2 research activity.
REC name
North East - Newcastle & North Tyneside 1 Research Ethics Committee
REC reference
15/NE/0024
Date of REC Opinion
26 Mar 2015
REC opinion
Further Information Favourable Opinion