New Methods of Detecting Problems in Pregnancy - Sample Bank - 2019

• Research type

  Research Tissue Bank

• IRAS ID

  261669

• Research summary

  New Methods of Detecting Problems in Pregnancy - Sample Bank

• REC name

  South Central - Oxford C Research Ethics Committee

• REC reference

  19/SC/0360

• Date of REC Opinion

  9 Sep 2019

• REC opinion

  Favourable Opinion

• Data collection arrangements

  Blood samples will be collected from pregnant women and their partners. The data collected will include clinical information about the pregnancy and pregnancy outcome. Samples are being collected from couples with both normal and complicated pregnancies and written consent is obtained. All women attending the clinics where recruitment will take place are given a patient information leaflet. A member of the clinical or research team will discuss the study. If the woman (and partner) express interest they will be given the opportunity to go through the information leaflet, ask any questions and discuss the study in more detail before being invited to sign the consent form.

• Research programme

  The sample bank will be used for the development of tests for the non-invasive prenatal diagnosis of genetic or chromosomal abnormalities in the fetus, or for the detection of pregnancies at increased risk of obstetric complications which jeopardise fetal well-being. The development of non-invasive tests for diagnosis and screening will enable safer delivery of prenatal diagnosis, avoiding the risk of miscarriage associated with invasive tests, and potentially improve early detection of serious pregnancy complications.

• Storage license

  12654

• RTBTitle

  New Methods of Detecting Problems in Pregnancy - Sample Bank

• Establishment organisation

  Great Ormond Street Hospital NHS Foundation Trust

• Establishment organisation address

  Barclay House

  37 Queen Square

  London

  WC1N 3BH