Neuroimaging study of borderline personality disorder

• Research type

  Research Study

• Full title

  The impact of treatment for borderline personality disorder: a neuroimaging study of social and psychomotor function.

• IRAS ID

  166486

• Contact name

  Kate Saunders

• Contact email

  kate.saunders@psych.ox.ac.uk

• Sponsor organisation

  University Of Oxford

• Duration of Study in the UK

  1 years, 0 months, 0 days

• Research summary

  We are interested in the impact of group psychotherapy (currently the recommended treatment for BPD on the behaviour and underlying neural mechanisms of people with borderline personality disorder. We will also compare them to a healthy control group.
  In this study we will use behavioral measures as well as the non-invasive neuroimaging techniques magnetic resonance imaging (MRI) and magnetoencephalography (MEG) to record people’s brain activity. MRI uses magnetic fields to create structural and functional images of the brain. MEG measures magnetic fields produced by brain activity from the surface of the scalp.
  We will recruit male and female participants with no upper age limit. Borderline participants will be identified by the Oxfordshire Complex Needs Service. Healthy controls will be recruited using advertisements in the local press and online.
  This study will enhance our understanding of the neural; mechanisms underlying social cooperation, and responses to negative events in BPD and allow an objective and informed method for assessing treatment outcome. It may also provide additional targets for psychological intervention

• REC name

  South Central - Oxford B Research Ethics Committee

• REC reference

  14/SC/1430

• Date of REC Opinion

  20 Jan 2015

• REC opinion

  Further Information Favourable Opinion