Neonatal Lung MRI in BPD - NIMROD A
Research type
Research Study
Full title
Structural and Functional Lung Magnetic Resonance Imaging of Bronchopulmonary Dysplasia on the Neonatal Unit.
IRAS ID
352325
Contact name
Porus Bustani
Contact email
Sponsor organisation
Sheffield Teachings Hospitals NHS Foundation Trust
Duration of Study in the UK
1 years, 5 months, 17 days
Research summary
When babies are born very early, their lungs have not developed properly and often they need help to breathe. The extra help we give them to breathe, along with infections and other reasons can cause damage to their lungs. The combination of stopping their lungs from developing properly due to being born very early, and the damage caused by helping them to breathe, and them being exposed to the outside world is called bronchopulmonary dysplasia (BPD).
BPD can range from being mild, (where babies do not need to be on oxygen by the time they go home) to severe or even life threatening (where they need lots of breathing support, even at home).Currently the only way to look at their lungs in detail is with a CT scan, this exposes them to harmful radiation. Our study aims to look at babies’ lungs in detail using an MRI scan. MRI does not use any harmful radiation and can also give us more information than CT on how well their lungs are working.
We will aim to do MRI scans on 40-50 babies born early (<32 weeks) with and without BPD.REC name
West Midlands - Solihull Research Ethics Committee
REC reference
25/WM/0120
Date of REC Opinion
24 Jul 2025
REC opinion
Further Information Favourable Opinion