NeoAdapt 1

  • Research type

    Research Study

  • Full title

    NeoAdapt 1 Study: Study of circulatory adaptation in newborn infants after birth

  • IRAS ID

    145159

  • Contact name

    Liam Mahoney

  • Contact email

    l.mahoney@doctors.org.uk

  • Sponsor organisation

    Brighton & Sussex University Hospitals NHS Trust

  • Clinicaltrials.gov Identifier

    NCT02047916

  • Research summary

    When babies are born the way their heart pumps blood around the body has to adapt from one that is in the womb that relies on the placenta to one that is self sufficient. Studies in premature babies have shown that this adaptation does not always happen quickly after birth and can interfere with the baby getting an adequate blood supply to their vital organs including the brain. This is very important as research has shown that the later development of the child is likely to be better if we can improve this blood supply.

    The problem we face is that we are not sure of the best way to measure blood supply in babies admitted to the neonatal intensive care unit. In this project we are going to investigate two new non-invasive methods of checking a babies blood supply known as superior vena cava flow and the pleth variability index to try and improve the way clinicians identify and treat infants who need help with their blood supply.

  • REC name

    London - City & East Research Ethics Committee

  • REC reference

    14/LO/0317

  • Date of REC Opinion

    23 Apr 2014

  • REC opinion

    Further Information Favourable Opinion