Nebulised HS in children with NMD and CP
Research type
Research Study
Full title
A Chart Review assessing the effects of Nebulised Hypertonic Saline on Respiratory-related complication in children with Neuromuscular disease and Cerebral Palsy
IRAS ID
243535
Contact name
Hui-Leng Tan
Contact email
Sponsor organisation
Imperial College London
Duration of Study in the UK
0 years, 6 months, 0 days
Research summary
Chart review of children with Neuromuscular disease or Cerebral Palsy who are cared for in the Royal Brompton Hospital and that have been treated with nebulised hypertonic saline for at least 12 months. Charts that meet criteria will be reviewed until May 2018. \n\nStudy duration: 6 months.\n\nInclusion criteria: Children with Neuromuscular disease or Cerebral Palsy who have their care at the Royal Brompton Hospital and are on treatment with nebulised Hypertonic Saline for at least 12 months.\n\nExclusion criteria: Children also diagnosed with Cystic Fibrosis. \n\nTo further complement data from hospital records, two questionnaires will be applied. Parents of children who meet criteria will be asked to complete the following questionnaires: 1) The National Health and Nutrition Examination Survey (NHANES) for Hospitalisation and access to are – HUQ.010; and 2) Questionnaire on Hypertonic Saline treatment. Children from 10 – 18 years will be asked to complete the Questionnaire on Hypertonic Saline treatment.\n\nAims:\n1) Explore whether treatment with nebulised Hypertonic Saline in children with Neuromuscular disease or Cerebral Palsy decreases respiratory-related complications.\n2) Evaluate whether the treatment with nebulised hypertonic saline in children with neuromuscular disease or cerebral palsy improves the ease of airway clearance. \n3) Explore how parents of children with Neuromuscular disease and children with Cerebral Palsy perceive the treatment with nebulised hypertonic saline compared with previous management. \n
REC name
Yorkshire & The Humber - Leeds West Research Ethics Committee
REC reference
18/YH/0103
Date of REC Opinion
1 Jun 2018
REC opinion
Further Information Favourable Opinion