NDDC Research Tissue Bank

• Research type

  Research Tissue Bank

• IRAS ID

  345256

• Research summary

  The Nottingham Digestive Diseases Centre Research Tissue Bank

• REC name

  Wales REC 5

• REC reference

  24/WA/0326

• Date of REC Opinion

  16 Jan 2025

• REC opinion

  Further Information Favourable Opinion

• Data collection arrangements

  Samples will be obtained from adults (healthy volunteers & patients with diagnosed with liver or gastrointestinal disorders) who are research participants and also from patients attending Nottingham University Hospitals NHS Trust as part of their standard clinical care. Samples will be collected with informed written consent either as surplus to clinical diagnostics or as additional research samples.
  Samples of blood, stool, urine, saliva, skin swabs and digestive system tissue from clinical procedures will be collected and stored. Samples may be fresh or preserved and may be processed to separate blood serum, plasma and cell types and extract metabolites, DNA or RNA.
  Basic demographic data will be recorded (including ethnicity, smoking and alcohol status). Medical information will also be documented (diagnosis, treatment and outcome).
  Researchers are not permitted to re-contact participants to obtain further samples or data.
  Samples/tissue will be stored within the Nottingham Digestive Diseases Centre, Queens Medical Centre, Nottingham, under University of Nottingham HTA licence: 12265.

• Research programme

  Researchers within The Nottingham Digestive Diseases Centre (https://www.nottingham.ac.uk/research/groups/giandliverdiseases/index.aspx) and NIHR Nottingham Biomedical Research Centre (https://nottinghambrc.nihr.ac.uk/) and collaborators, will be able to request samples following review by access committee. This will enable new hypotheses to be tested through pilot studies and new technologies to be developed/optimised and biomarkers to be identified/assessed as part of translational research for improved patient care, aligned with the aims of the research centres.

• Storage license

  12265

• RTBTitle

  The Nottingham Digestive Diseases Centre Research Tissue Bank

• Establishment organisation

  Nottingham Digestive Diseases Centre

• Establishment organisation address

  University of Nottingham

  E Floor West Block, Queens Medical Centre

  Nottingham

  NG7 2UH