NATASHA Study

  • Research type

    Research Study

  • Full title

    Using Commonly Available Food Products To Treat Food Allergy

  • IRAS ID

    310316

  • Contact name

    Syed Hasan Arshad

  • Contact email

    s.h.arshad@soton.ac.uk

  • Clinicaltrials.gov Identifier

    NCT05503446

  • Duration of Study in the UK

    4 years, 0 months, 30 days

  • Research summary

    Food allergy is common in childhood and in many cases, continues into teenage years in up to half of affected children. To avoid allergic reactions people with food allergies, need to avoid their trigger food(s) in their diet. This can have a negative impact on nutrition and quality of life, limiting food choices, affecting shopping and their social life due to anxiety over the potential for severe reactions due to accidental exposure.

    Currently, there is no cure for food allergy. Research has shown that for some foods (such as peanut and cow’s milk), gradual exposure to the allergic food – under strict medical supervision – beginning with very low doses of the food can allow allergic individuals to eat that food safely, without reacting. This is called desensitisation, and the term we use is called Oral ImmunoTherapy (OIT).

    In this study, we want to demonstrate that OIT using commonly available foods can be used safely to treat children and young people with peanut or cow’s milk allergy and collect data to demonstrate that this can be cost-effective in the NHS setting.

  • REC name

    South Central - Hampshire B Research Ethics Committee

  • REC reference

    22/SC/0135

  • Date of REC Opinion

    7 Jun 2022

  • REC opinion

    Further Information Favourable Opinion