Myotrace CT Correlation
Research type
Research Study
Full title
Myotrace Computed Tomography Restrospective Analysis
IRAS ID
210780
Contact name
Nicholas Hart
Contact email
Sponsor organisation
Guys and St Thomas' NHS Foundation Trust
Duration of Study in the UK
0 years, 4 months, 17 days
Research summary
Patients admitted to hospital with acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD) are at risk of significant in-hospital morbidity and mortality. Current markers of treatment success involve the integration of basic physiological variables (respiratory rate, heart rate, oxygen saturations), clinical examination and patient reported symptoms changes. Whilst the use of these physiological parameters are gold standard there remains concern that patient deterioration is often not detected and escalated effectively. This has led to the development and implementation of a range of clinical physiological composite scores such as the medical early warning score or the NHS national early warning scores. However, these scores have been validated in general rather than specific populations and there are concerns regarding their use in respiratory patient groups. The use of the parasternal intercostal muscle EMG (EMGpara) has been reported to track clinical change and identify treatment failure during hospital admissions with acute exacerbations of COPD (AECOPD) in selected and unselected cohorts. We have shown recently that the EMGpara at discharge was able to predict safe discharge following an AECOPD.
The data on EMGpara that we have collected show a great variability at admission. We hypothesize that this variability may be related to patients anthropometric and respiratory features.REC name
London - Harrow Research Ethics Committee
REC reference
16/LO/1772
Date of REC Opinion
25 Oct 2016
REC opinion
Further Information Favourable Opinion