Myometrium Study Version 1

• Research type

  Research Study

• Full title

  The Myometrium Study: Understanding the Mechanisms Controlling Human Uterine Muscle Function

• IRAS ID

  252837

• Contact name

  Rachel M Tribe

• Contact email

  rachel.tribe@kcl.ac.uk

• Sponsor organisation

  King's College London

• Clinicaltrials.gov Identifier

  7843, UKCRN

• Duration of Study in the UK

  4 years, 1 months, 14 days

• Research summary

  We do not fully understand the mechanisms that initiate contractions, nor do we understand why the muscles of the uterus are in a less contractile state during the majority of pregnancy. The aim of this study is to investigate how and why labour occurs preterm, at term and post term. To achieve this we will be collecting samples of the uterine muscle wall (myometrium) at caesarean section and hysterectomy. These samples will be anonymised and used immediately or stored for analysis of various potential factors that may affect labour.

• REC name

  London - Central Research Ethics Committee

• REC reference

  19/LO/1827

• Date of REC Opinion

  22 Jan 2020

• REC opinion

  Further Information Favourable Opinion