Myocarditis Symptoms Study v1.0
Research type
Research Study
Full title
Evaluating the long-term symptoms, management, and prognosis of patients with inflammatory cardiac conditions.
IRAS ID
334919
Contact name
Daniel Bromage
Contact email
Sponsor organisation
King's College London
Duration of Study in the UK
2 years, 0 months, 0 days
Research summary
Inflammation is the body’s natural response to injury or infection, where the immune system is activated to help repair damage or fight off harmful invaders. However, when inflammation happens in the heart muscle (a condition called myocarditis), it can cause or worsen several heart problems, including heart attacks and heart failure.
Research into general anti-inflammatory treatments, designed to reduce this immune response, has often been unsuccessful because inflammation affects people in very different ways, leading to a wide variety of symptoms. People with myocarditis may experience chest pain, a racing or irregular heartbeat, and breathlessness, but others might only have vague symptoms like extreme tiredness, fainting, or flu-like illness before or after the condition starts.
Patients are often advised to avoid intense exercise for six months, but there isn’t strong evidence to back up this recommendation. This questionnaire study will look at symptoms before and after the condition develops, as well as how well patients follow exercise advice. We hope this will help identify patients who could benefit from personalised treatments to better manage inflammation and tailored exercise recommendations.
REC name
West Midlands - Solihull Research Ethics Committee
REC reference
25/WM/0044
Date of REC Opinion
21 Mar 2025
REC opinion
Further Information Favourable Opinion